Richard Notebaart

 

 

 

 

My research is about i) evolutionary systems biology of metabolism to study adaptations of microorganisms (e.g., E. coli) and ii) systems-level understanding of mitochondria phenotypes in health and disease.

Both topics have a strong association between computational and experimental systems biology approaches. Recently, we received a major funding for a new exciting "Center for Systems Biology and Bioenergetics" (CSBB - http://www.csb-bioenergetics.nl/), which will be part of the Radboud University Nijmegen Medical Centre in The Netherlands.

We are looking for at least two Postdoc candidates on computational systems biology. One of the two Postdocs will work on small-scale dynamic models and the other one on genome-scale stoichiometric flux models of human and mouse metabolism.

We therefore support applications of ambitious and motivated Postdocs who want to work in computational systems biology within our new CSBB. A strong background in bioinformatics, computer science, and/or cell biology (biochemistry) science will be needed. Please send me your CV, list of publications and two reference letters.

The CSBB is a highly collaborative effort of computational biologists, experimentalists and clinicians to understand genetic disorders in  energy metabolism. We want to construct and combine small-scale dynamic models of mitochiondrial metabolism and genome-scale stoichiometric flux models of human and mouse metabolism. These models will be constructed, extended and validated by unique experimental metabolomics, proteomics and gene expression data produced by the CSBB. All CSBB members work together on the standardization of measurements to ensure a high quality data to be used for the computational models. Additionally, models of patients and healthy people (or mice) will be compared with the aim of explaining disorders and to define medical interventions.

Please visit my personal website for more information.

 

 

 

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